Negative Coupling as a Mechanism for Signal Propagation between C2 Domains of Synaptotagmin I

Synaptotagmin I (Syt I) is a vesicle-localized protein implicated in sensing the calcium influx that triggers fast synchronous release of neurotransmitter. How Syt I utilizes its two C2 domains to integrate signals and mediate neurotransmission has continued to be a controversial area of research, t...

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Detalles Bibliográficos
Autores principales: Fealey, Michael E., Gauer, Jacob W., Kempka, Sarah C., Miller, Katie, Nayak, Kamakshi, Sutton, R. Bryan, Hinderliter, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465270/
https://www.ncbi.nlm.nih.gov/pubmed/23071627
http://dx.doi.org/10.1371/journal.pone.0046748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465270/
https://www.ncbi.nlm.nih.gov/pubmed/23071627
http://dx.doi.org/10.1371/journal.pone.0046748

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