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Negative Coupling as a Mechanism for Signal Propagation between C2 Domains of Synaptotagmin I
Synaptotagmin I (Syt I) is a vesicle-localized protein implicated in sensing the calcium influx that triggers fast synchronous release of neurotransmitter. How Syt I utilizes its two C2 domains to integrate signals and mediate neurotransmission has continued to be a controversial area of research, t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465270/ https://www.ncbi.nlm.nih.gov/pubmed/23071627 http://dx.doi.org/10.1371/journal.pone.0046748 |