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LH and hCG Action on the Same Receptor Results in Quantitatively and Qualitatively Different Intracellular Signalling

Human luteinizing hormone (hLH) and chorionic gonadotropin (hCG) act on the same receptor (LHCGR) but it is not known whether they elicit the same cellular and molecular response. This study compares for the first time the activation of cell-signalling pathways and gene expression in response to hLH...

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Detalles Bibliográficos
Autores principales: Casarini, Livio, Lispi, Monica, Longobardi, Salvatore, Milosa, Fabiola, La Marca, Antonio, Tagliasacchi, Daniela, Pignatti, Elisa, Simoni, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465272/
https://www.ncbi.nlm.nih.gov/pubmed/23071612
http://dx.doi.org/10.1371/journal.pone.0046682