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Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

Direct comparison of protein components from human and mouse excitatory synapses is important for determining the suitability of mice as models of human brain disease and to understand the evolution of the mammalian brain. The postsynaptic density is a highly complex set of proteins organized into m...

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Detalles Bibliográficos
Autores principales: Bayés, Àlex, Collins, Mark O., Croning, Mike D. R., van de Lagemaat, Louie N., Choudhary, Jyoti S., Grant, Seth G. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465276/
https://www.ncbi.nlm.nih.gov/pubmed/23071613
http://dx.doi.org/10.1371/journal.pone.0046683