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Omega-3 Polyunsaturated Fatty Acids Antagonize Macrophage Inflammation via Activation of AMPK/SIRT1 Pathway

Macrophages play a key role in obesity-induced inflammation. Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exert anti-inflammatory functions in both humans and animal models, but the exact cellular signals mediating the beneficial effects...

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Detalles Bibliográficos
Autores principales: Xue, Bingzhong, Yang, Zhenggang, Wang, Xianfeng, Shi, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465287/
https://www.ncbi.nlm.nih.gov/pubmed/23071533
http://dx.doi.org/10.1371/journal.pone.0045990