IRF1 and NF-kB Restore MHC Class I-Restricted Tumor Antigen Processing and Presentation to Cytotoxic T Cells in Aggressive Neuroblastoma

Neuroblastoma (NB), the most common solid extracranial cancer of childhood, displays a remarkable low expression of Major Histocompatibility Complex class I (MHC-I) and Antigen Processing Machinery (APM) molecules, including Endoplasmic Reticulum (ER) Aminopeptidases, and poorly presents tumor antig...

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Detalles Bibliográficos
Autores principales: Lorenzi, Silvia, Forloni, Matteo, Cifaldi, Loredana, Antonucci, Chiara, Citti, Arianna, Boldrini, Renata, Pezzullo, Marco, Castellano, Aurora, Russo, Vincenzo, van der Bruggen, Pierre, Giacomini, Patrizio, Locatelli, Franco, Fruci, Doriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465322/
https://www.ncbi.nlm.nih.gov/pubmed/23071666
http://dx.doi.org/10.1371/journal.pone.0046928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465322/
https://www.ncbi.nlm.nih.gov/pubmed/23071666
http://dx.doi.org/10.1371/journal.pone.0046928

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