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IRF1 and NF-kB Restore MHC Class I-Restricted Tumor Antigen Processing and Presentation to Cytotoxic T Cells in Aggressive Neuroblastoma

Neuroblastoma (NB), the most common solid extracranial cancer of childhood, displays a remarkable low expression of Major Histocompatibility Complex class I (MHC-I) and Antigen Processing Machinery (APM) molecules, including Endoplasmic Reticulum (ER) Aminopeptidases, and poorly presents tumor antig...

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Detalles Bibliográficos
Autores principales:	Lorenzi, Silvia, Forloni, Matteo, Cifaldi, Loredana, Antonucci, Chiara, Citti, Arianna, Boldrini, Renata, Pezzullo, Marco, Castellano, Aurora, Russo, Vincenzo, van der Bruggen, Pierre, Giacomini, Patrizio, Locatelli, Franco, Fruci, Doriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465322/ https://www.ncbi.nlm.nih.gov/pubmed/23071666 http://dx.doi.org/10.1371/journal.pone.0046928

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