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Plasma Uric Acid Levels Correlate with Inflammation and Disease Severity in Malian Children with Plasmodium falciparum Malaria

BACKGROUND: Plasmodium falciparum elicits host inflammatory responses that cause the symptoms and severe manifestations of malaria. One proposed mechanism involves formation of immunostimulatory uric acid (UA) precipitates, which are released from sequestered schizonts into microvessels. Another inv...

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Detalles Bibliográficos
Autores principales: Lopera-Mesa, Tatiana M., Mita-Mendoza, Neida K., van de Hoef, Diana L., Doumbia, Saibou, Konaté, Drissa, Doumbouya, Mory, Gu, Wenjuan, Traoré, Karim, Diakité, Seidina A. S., Remaley, Alan T., Anderson, Jennifer M., Rodriguez, Ana, Fay, Michael P., Long, Carole A., Diakité, Mahamadou, Fairhurst, Rick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465329/
https://www.ncbi.nlm.nih.gov/pubmed/23071567
http://dx.doi.org/10.1371/journal.pone.0046424