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Plasma Uric Acid Levels Correlate with Inflammation and Disease Severity in Malian Children with Plasmodium falciparum Malaria
BACKGROUND: Plasmodium falciparum elicits host inflammatory responses that cause the symptoms and severe manifestations of malaria. One proposed mechanism involves formation of immunostimulatory uric acid (UA) precipitates, which are released from sequestered schizonts into microvessels. Another inv...
Autores principales: | Lopera-Mesa, Tatiana M., Mita-Mendoza, Neida K., van de Hoef, Diana L., Doumbia, Saibou, Konaté, Drissa, Doumbouya, Mory, Gu, Wenjuan, Traoré, Karim, Diakité, Seidina A. S., Remaley, Alan T., Anderson, Jennifer M., Rodriguez, Ana, Fay, Michael P., Long, Carole A., Diakité, Mahamadou, Fairhurst, Rick M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465329/ https://www.ncbi.nlm.nih.gov/pubmed/23071567 http://dx.doi.org/10.1371/journal.pone.0046424 |
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