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Pre-Diabetes Augments Neuropeptide Y(1)- and α(1)-Receptor Control of Basal Hindlimb Vascular Tone in Young ZDF Rats

BACKGROUND: Peripheral vascular disease in pre-diabetes may involve altered sympathetically-mediated vascular control. Thus, we investigated if pre-diabetes modifies baseline sympathetic Y(1)-receptor (Y(1)R) and α(1)-receptor (α(1)R) control of hindlimb blood flow (Q(fem)) and vascular conductance...

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Detalles Bibliográficos
Autores principales: Novielli, Nicole M., Al-Khazraji, Baraa K., Medeiros, Philip J., Goldman, Daniel, Jackson, Dwayne N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465334/
https://www.ncbi.nlm.nih.gov/pubmed/23071607
http://dx.doi.org/10.1371/journal.pone.0046659