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Pregnancy imprints regulatory memory that sustains anergy to fetal antigen

Pregnancy is an intricately orchestrated process where immune effector cells with fetal specificity are selectively silenced. This requires the sustained expansion of immune suppressive maternal Foxp3(+) regulatory T cells (Tregs), because even transient partial ablation triggers fetal-specific effe...

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Detalles Bibliográficos
Autores principales: Rowe, Jared H., Ertelt, James M., Xin, Lijun, Way, Sing Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465465/
https://www.ncbi.nlm.nih.gov/pubmed/23023128
http://dx.doi.org/10.1038/nature11462