5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary

5-hydroxymethylcytosine (5-hmC), a derivative of 5-methylcytosine (5-mC), is abundant in the brain for unknown reasons. Our goal was to characterize the genomic distribution of 5-hmC and 5-mC in human and mouse tissues. We assayed 5-hmC using glucosylation coupled with restriction enzyme digestion,...

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Detalles Bibliográficos
Autores principales: Khare, Tarang, Pai, Shraddha, Koncevicius, Karolis, Pal, Mrinal, Kriukiene, Edita, Liutkeviciute, Zita, Irimia, Manuel, Jia, Peixin, Ptak, Carolyn, Xia, Menghang, Tice, Raymond, Tochigi, Mamoru, Moréra, Solange, Nazarians, Anaies, Belsham, Denise, Wong, Albert H. C., Blencowe, Benjamin J., Wang, Sun Chong, Kapranov, Philipp, Kustra, Rafal, Labrie, Viviane, Klimasauskas, Saulius, Petronis, Arturas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465469/
https://www.ncbi.nlm.nih.gov/pubmed/22961382
http://dx.doi.org/10.1038/nsmb.2372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465469/
https://www.ncbi.nlm.nih.gov/pubmed/22961382
http://dx.doi.org/10.1038/nsmb.2372

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