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Membrane Fission Is Promoted by Insertion of Amphipathic Helices and Is Restricted by Crescent BAR Domains

Shallow hydrophobic insertions and crescent-shaped BAR scaffolds promote membrane curvature. Here, we investigate membrane fission by shallow hydrophobic insertions quantitatively and mechanistically. We provide evidence that membrane insertion of the ENTH domain of epsin leads to liposome vesiculat...

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Detalles Bibliográficos
Autores principales: Boucrot, Emmanuel, Pick, Adi, Çamdere, Gamze, Liska, Nicole, Evergren, Emma, McMahon, Harvey T., Kozlov, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465558/
https://www.ncbi.nlm.nih.gov/pubmed/22464325
http://dx.doi.org/10.1016/j.cell.2012.01.047