Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1 (DNMT1)

To examine the roles of epigenetic modulation on hair follicle regeneration, we generated mice with a K14Cre-mediated loss of DNA methyltransferase (DNMT) 1. The mutant shows an uneven epidermal thickness and alterations in hair follicle size. When formed, hair follicle architecture and differentiat...

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Detalles Bibliográficos
Autores principales: Li, Ji, Jiang, Ting-Xin, Hughes, Michael W., Wu, Ping, Widelitz, Randall B, Fan, Guoping, Chuong, Cheng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465630/
https://www.ncbi.nlm.nih.gov/pubmed/22763785
http://dx.doi.org/10.1038/jid.2012.206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465630/
https://www.ncbi.nlm.nih.gov/pubmed/22763785
http://dx.doi.org/10.1038/jid.2012.206

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