Cargando…

Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1 (DNMT1)

To examine the roles of epigenetic modulation on hair follicle regeneration, we generated mice with a K14Cre-mediated loss of DNA methyltransferase (DNMT) 1. The mutant shows an uneven epidermal thickness and alterations in hair follicle size. When formed, hair follicle architecture and differentiat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ji, Jiang, Ting-Xin, Hughes, Michael W., Wu, Ping, Widelitz, Randall B, Fan, Guoping, Chuong, Cheng-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465630/ https://www.ncbi.nlm.nih.gov/pubmed/22763785 http://dx.doi.org/10.1038/jid.2012.206

Ejemplares similares

Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis
por: Hughes, Michael W., et al.
Publicado: (2013)

Regional Specific Differentiation of Integumentary Organs: Regulation of Gene Clusters within the Avian Epidermal Differentiation Complex and Impacts of SATB2 Overexpression
por: Lin, Gee-Way, et al.
Publicado: (2021)

Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase
por: Goyal, Rachna, et al.
Publicado: (2006)

The ‘de novo’ DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium
por: Elliott, Ellen N, et al.
Publicado: (2016)

The methyltransferase domain of DNMT1 is an essential domain in acute myeloid leukemia independent of DNMT3A mutation
por: Bhogal, Balpreet, et al.
Publicado: (2022)

Structure of DNA methyltransferases DNMT3A/DNMT3B bound to a nucleosome
por: Xu, Ting-Hai, et al.
Publicado: (2020)

DNA METHYLATION BY DNMT1 AND DNMT3b METHYLTRANSFERASES IS DRIVEN BY THE MUC1-C ONCOPROTEIN IN HUMAN CARCINOMA CELLS
por: Rajabi, Hasan, et al.
Publicado: (2016)

Comprehensive molecular and cellular studies suggest avian scutate scales are secondarily derived from feathers, and more distant from reptilian scales
por: Wu, Ping, et al.
Publicado: (2018)

DNA methyltransferase expression (DNMT1, DNMT3a and DNMT3b) as a potential biomarker for anti-VEGF diabetic macular edema response
por: Camacho, Pedro, et al.
Publicado: (2023)

DNA Methyltransferase 1 (DNMT1) Function Is Implicated in the Age-Related Loss of Cortical Interneurons
por: Hahn, Anne, et al.
Publicado: (2020)

DNA Methyltransferase 1 (DNMT1) Acts on Neurodegeneration by Modulating Proteostasis-Relevant Intracellular Processes
por: Bayer, Cathrin, et al.
Publicado: (2020)

On the Evolutionary Origin of Eukaryotic DNA Methyltransferases and Dnmt2
por: Jurkowski, Tomasz P., et al.
Publicado: (2011)

On the accuracy of the epigenetic copy machine: comprehensive specificity analysis of the DNMT1 DNA methyltransferase
por: Adam, Sabrina, et al.
Publicado: (2023)

DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology
por: Saini, Sunil Kumar, et al.
Publicado: (2017)

The Roles of DNA Methyltransferases 1 (DNMT1) in Regulating Sexual Dimorphism in the Cotton Mealybug, Phenacoccus solenopsis
por: Omar, Mohamed A.A., et al.
Publicado: (2020)

Design and synthesis of water-soluble grifolin prodrugs for DNA methyltransferase 1 (DNMT1) down-regulation
por: Wang, Liguo, et al.
Publicado: (2021)

Diverse feather shape evolution enabled by coupling anisotropic signalling modules with self-organizing branching programme
por: Li, Ang, et al.
Publicado: (2017)

Overexpression of DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) And DNA (Cytosine-5)-Methyltransferase 3A (DNMT3A) Is Associated with Aggressive Behavior and Hypermethylation of Tumor Suppressor Genes in Human Pituitary Adenomas
por: Ma, Hou-Shi, et al.
Publicado: (2018)

Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
por: Lei, Mingxing, et al.
Publicado: (2023)

Histone Methyltransferases SUV39H1 and G9a and DNA Methyltransferase DNMT1 in Penumbra Neurons and Astrocytes after Photothrombotic Stroke
por: Sharifulina, Svetlana, et al.
Publicado: (2021)

Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
por: Jurkowska, Renata Z., et al.
Publicado: (2008)

Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification
por: Lai, Yung-Chih, et al.
Publicado: (2018)

Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
por: Espada, Jesús, et al.
Publicado: (2007)

miR-148-3p Inhibits Growth of Glioblastoma Targeting DNA Methyltransferase-1 (DNMT1)
por: Li, Yongtao, et al.
Publicado: (2019)

Genome-wide methylation data from R1 (wild-type) and the transgenic Dnmt1(Tet/Tet) mouse embryonic stem cells overexpressing DNA methyltransferase 1 (DNMT1)
por: Saxena, Sonal, et al.
Publicado: (2020)

Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase
por: Stepper, Peter, et al.
Publicado: (2017)

RNA–Mediated Epigenetic Heredity Requires the Cytosine Methyltransferase Dnmt2
por: Kiani, Jafar, et al.
Publicado: (2013)

No Detectable Effect of the DNA Methyltransferase DNMT2 on Drosophila Meiotic Recombination
por: Heil, Caiti S. Smukowski
Publicado: (2014)

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors
por: Laranjeira, Angelo B. A., et al.
Publicado: (2023)

In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1
por: Miletić, Vedran, et al.
Publicado: (2017)

Inhibition of DNMT1 methyltransferase activity via glucose-regulated O-GlcNAcylation alters the epigenome
por: Shin, Heon, et al.
Publicado: (2023)

DNA Methyltransferase 1 (DNMT1) Shapes Neuronal Activity of Human iPSC-Derived Glutamatergic Cortical Neurons
por: Bachmann, Sarah, et al.
Publicado: (2021)

Regenerative hair waves in aging mice and extra-follicular modulators Follistatin, Dkk1 and Sfrp4
por: Chen, Chih-Chiang, et al.
Publicado: (2014)

The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice
por: Li, Gang, et al.
Publicado: (2017)

Novel CLDN1 Deletion Associated with Ichthyosis, Sclerosing Cholangitis and Acquired Alopecia
por: ALSAFRI, Maleha S., et al.
Publicado: (2020)

DNA Methyltransferase I (DNMT1) Inhibition Induces a p21 Dependent Cell Cycle Arrest
por: Young, Juan I., et al.
Publicado: (2001)

Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK
por: Bai, Jian, et al.
Publicado: (2016)

Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase
por: Dukatz, Michael, et al.
Publicado: (2020)

The DNA methyltransferase DNMT3A contributes to autophagy long-term memory
por: González-Rodríguez, Patricia, et al.
Publicado: (2020)

DNA Methylation-mediated Down-regulation of DNA Methyltransferase-1 (DNMT1) Is Coincident with, but Not Essential for, Global Hypomethylation in Human Placenta
por: Novakovic, Boris, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_2c66up9d8ll9evkuos0chgjtj4