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RET is a potential tumor suppressor gene in colorectal cancer

Cancer arises as the consequence of mutations and epigenetic alterations that activate oncogenes and inactivate tumor suppressor genes. Through a genome-wide screen for methylated genes in colon neoplasms, we identified aberrantly methylated RET in colorectal cancer. RET, a transmembrane receptor ty...

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Detalles Bibliográficos
Autores principales: Luo, Yanxin, Tsuchiya, Karen D., Park, Dong Il, Fausel, Rebecca, Kanngurn, Samornmas, Welcsh, Piri, Dzieciatkowski, Slavomir, Wang, Jianping, Grady, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465636/
https://www.ncbi.nlm.nih.gov/pubmed/22751117
http://dx.doi.org/10.1038/onc.2012.225