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Cotinine-conjugated aptamer/anti-cotinine antibody complexes as a novel affinity unit for use in biological assays

Aptamers are synthetic, relatively short (e.g., 20-80 bases) RNA or ssDNA oligonucleotides that can bind targets with high affinity and specificity, similar to antibodies, because they can fold into unique, three-dimensional shapes. For use in various assays and experiments, aptamers have been conju...

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Detalles Bibliográficos
Autores principales: Park, Sunyoung, Hwang, Dobin, Chung, Junho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465749/
https://www.ncbi.nlm.nih.gov/pubmed/22809871
http://dx.doi.org/10.3858/emm.2012.44.9.063