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Donor Satellite Cell Engraftment is Significantly Augmented When the Host Niche is Preserved and Endogenous Satellite Cells are Incapacitated

Stem cell transplantation is already in clinical practice for certain genetic diseases and is a promising therapy for dystrophic muscle. We used the mdx mouse model of Duchenne muscular dystrophy to investigate the effect of the host satellite cell niche on the contribution of donor muscle stem cell...

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Detalles Bibliográficos
Autores principales: Boldrin, Luisa, Neal, Alice, Zammit, Peter S, Muntoni, Francesco, Morgan, Jennifer E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465801/
https://www.ncbi.nlm.nih.gov/pubmed/22730231
http://dx.doi.org/10.1002/stem.1158