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Donor Satellite Cell Engraftment is Significantly Augmented When the Host Niche is Preserved and Endogenous Satellite Cells are Incapacitated
Stem cell transplantation is already in clinical practice for certain genetic diseases and is a promising therapy for dystrophic muscle. We used the mdx mouse model of Duchenne muscular dystrophy to investigate the effect of the host satellite cell niche on the contribution of donor muscle stem cell...
Autores principales: | Boldrin, Luisa, Neal, Alice, Zammit, Peter S, Muntoni, Francesco, Morgan, Jennifer E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465801/ https://www.ncbi.nlm.nih.gov/pubmed/22730231 http://dx.doi.org/10.1002/stem.1158 |
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