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Modulation of Preactivation of PPAR-β on Memory and Learning Dysfunction and Inflammatory Response in the Hippocampus in Rats Exposed to Global Cerebral Ischemia/Reperfusion

The aim of this study is to investigate the neuroprotective effects and relevant mechanism of GW0742, an agonist of PPAR-β, after global cerebral ischemia-reperfusion injury (GCIRI) in rats. The rats showed memory and cognitive impairment and cytomorphological change in the hippocampus neurons follo...

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Detalles Bibliográficos
Autores principales: Kuang, Ge, He, Qin, Zhang, Yunmei, Zhuang, Ruichun, Xiang, Anling, Jiang, Qingsong, Luo, Ying, Yang, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465902/
https://www.ncbi.nlm.nih.gov/pubmed/23056034
http://dx.doi.org/10.1155/2012/209794