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Exenatide Pretreatment Improved Graft Function in Nonhuman Primate Islet Recipients Compared to Treatment after Transplant Only

The GLP-1 receptor agonist, exenatide, has previously been shown to improve insulin secretion, protect beta cells from apoptosis, and promote beta cell regeneration. We propose that pretreatment with exenatide will promote islet graft survival and improve graft function. Pancreatectomized cynomolgus...

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Detalles Bibliográficos
Autores principales: Buss, Jill L., Rajab, Amer, Essig, Elizabeth D., Bergdall, Valerie K., Wang, Jie, Osei, Kwame
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465909/
https://www.ncbi.nlm.nih.gov/pubmed/23056916
http://dx.doi.org/10.1155/2012/382518