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Exenatide Pretreatment Improved Graft Function in Nonhuman Primate Islet Recipients Compared to Treatment after Transplant Only
The GLP-1 receptor agonist, exenatide, has previously been shown to improve insulin secretion, protect beta cells from apoptosis, and promote beta cell regeneration. We propose that pretreatment with exenatide will promote islet graft survival and improve graft function. Pancreatectomized cynomolgus...
Autores principales: | Buss, Jill L., Rajab, Amer, Essig, Elizabeth D., Bergdall, Valerie K., Wang, Jie, Osei, Kwame |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465909/ https://www.ncbi.nlm.nih.gov/pubmed/23056916 http://dx.doi.org/10.1155/2012/382518 |
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