Cargando…
Simulation of Arrhythmogenic Effect of Rogue RyRs in Failing Heart by Using a Coupled Model
Cardiac cells with heart failure are usually characterized by impairment of Ca(2+) handling with smaller SR Ca(2+) store and high risk of triggered activities. In this study, we developed a coupled model by integrating the spatiotemporal Ca(2+) reaction-diffusion system into the cellular electrophys...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465912/ https://www.ncbi.nlm.nih.gov/pubmed/23056145 http://dx.doi.org/10.1155/2012/183978 |