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The Global Transcriptional Response of Isolated Human Islets of Langerhans to Glucagon-Like Peptide-1 Receptor Agonist Liraglutide

GLP-1 and its analog have been used in diabetes treatment; however, the direct alteration of gene expression profile in human islets induced by GLP-1 has not been reported. In present study, transcriptional gene expression in the liraglutide-treated human islets was analyzed with 12 human U133A chip...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoning, Tang, Yongming G., Wu, S. Vincent, Wang, Charles, Perfetti, Ricardo, Khoury, Nasif, Cai, Dehong, He, Fang, Su, Xiaogang, Go, Vay Liang W., Hui, Hongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465925/
https://www.ncbi.nlm.nih.gov/pubmed/23056957
http://dx.doi.org/10.5402/2012/608672