Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice

We have demonstrated that treating diet-induced obese (DIO) mice with the vasopeptidase inhibitor ilepatril improved neural function. Vasopeptidase inhibitors block angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) activity. We propose that increased activity of ACE and NEP contrib...

Descripción completa

Detalles Bibliográficos
Autores principales: Coppey, Lawrence, Lu, Bao, Gerard, Craig, Yorek, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465928/
https://www.ncbi.nlm.nih.gov/pubmed/23056927
http://dx.doi.org/10.1155/2012/326806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465928/
https://www.ncbi.nlm.nih.gov/pubmed/23056927
http://dx.doi.org/10.1155/2012/326806

Ejemplares similares