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Renal Podocyte Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin

Hyperglycemia promotes oxidative stress and hence generation of reactive oxygen species (ROS), which is known to play a crucial role in the pathogenesis of diabetic nephropathy. Metformin, an oral hypoglycemic drug, possesses antioxidant effects. The aim of this paper is to investigate the protectiv...

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Detalles Bibliográficos
Autores principales: Kim, Junghyun, Shon, Eunjin, Kim, Chan-Sik, Kim, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465985/
https://www.ncbi.nlm.nih.gov/pubmed/23056035
http://dx.doi.org/10.1155/2012/210821