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Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity

Glucagon-like peptide-1 (GLP-1) signaling modulates sweet-taste sensitivity in the mouse. Because circumvallate papillae (CVPs) express both GLP-1 and its receptor, a local regulation has been suggested. However, whether dietary lipids are involved in this regulation, as shown in the gut, is unknown...

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Detalles Bibliográficos
Autores principales: Martin, Céline, Passilly-Degrace, Patricia, Chevrot, Michaël, Ancel, Déborah, Sparks, Steven M., Drucker, Daniel J., Besnard, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465995/
https://www.ncbi.nlm.nih.gov/pubmed/22904345
http://dx.doi.org/10.1194/jlr.M025874