Cargando…

Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry

[Image: see text] Mycobacteria, including the pathogen Mycobacterium tuberculosis, use the non-mammalian disaccharide trehalose as a precursor for essential cell-wall glycolipids and other metabolites. Here we describe a strategy for exploiting trehalose metabolic pathways to label glycolipids in my...

Descripción completa

Detalles Bibliográficos
Autores principales: Swarts, Benjamin M., Holsclaw, Cynthia M., Jewett, John C., Alber, Marina, Fox, Douglas M., Siegrist, M. Sloan, Leary, Julie A., Kalscheuer, Rainer, Bertozzi, Carolyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466019/
https://www.ncbi.nlm.nih.gov/pubmed/22978752
http://dx.doi.org/10.1021/ja3062419