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TRIM38 Negatively Regulates TLR3-Mediated IFN-β Signaling by Targeting TRIF for Degradation

Toll-like receptors (TLRs) mediated immune response is crucial for combating pathogens and must be tightly controlled. Tripartite motif (TRIM) proteins are a family of proteins that is involved in a variety of biological and physiological processes. Some members of the TRIM family are important in t...

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Detalles Bibliográficos
Autores principales: Xue, Qinghua, Zhou, Zhuo, Lei, Xiaobo, Liu, Xinlei, He, Bin, Wang, Jianwei, Hung, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466175/
https://www.ncbi.nlm.nih.gov/pubmed/23056470
http://dx.doi.org/10.1371/journal.pone.0046825