Recombinant Acylation Stimulating Protein Administration to C3(−/−) Mice Increases Insulin Resistance via Adipocyte Inflammatory Mechanisms

BACKGROUND: Complement 3 (C3), a key component of the innate immune system, is involved in early inflammatory responses. Acylation stimulating protein (ASP; aka C3adesArg), a C3 cleavage product, is produced in adipose tissue and stimulates lipid storage. We hypothesized that, depending on the diet,...

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Detalles Bibliográficos
Autores principales: Munkonda, Mercedes Nancy, Lapointe, Marc, Miegueu, Pierre, Roy, Christian, Gauvreau, Danny, Richard, Denis, Cianflone, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466186/
https://www.ncbi.nlm.nih.gov/pubmed/23056509
http://dx.doi.org/10.1371/journal.pone.0046883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466186/
https://www.ncbi.nlm.nih.gov/pubmed/23056509
http://dx.doi.org/10.1371/journal.pone.0046883

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