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Recombinant Acylation Stimulating Protein Administration to C3(−/−) Mice Increases Insulin Resistance via Adipocyte Inflammatory Mechanisms
BACKGROUND: Complement 3 (C3), a key component of the innate immune system, is involved in early inflammatory responses. Acylation stimulating protein (ASP; aka C3adesArg), a C3 cleavage product, is produced in adipose tissue and stimulates lipid storage. We hypothesized that, depending on the diet,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466186/ https://www.ncbi.nlm.nih.gov/pubmed/23056509 http://dx.doi.org/10.1371/journal.pone.0046883 |