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Role of N-Terminal His(6)-Tags in Binding and Efficient Translocation of Polypeptides into Cells Using Anthrax Protective Antigen (PA)

It is of interest to define bacterial toxin biochemical properties to use them as molecular-syringe devices in order to deliver enzymatic activities into host cells. Binary toxins of the AB(7/8)-type are among the most potent and specialized bacterial protein toxins. The B subunits oligomerize to fo...

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Detalles Bibliográficos
Autores principales: Beitzinger, Christoph, Stefani, Caroline, Kronhardt, Angelika, Rolando, Monica, Flatau, Gilles, Lemichez, Emmanuel, Benz, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466187/
https://www.ncbi.nlm.nih.gov/pubmed/23056543
http://dx.doi.org/10.1371/journal.pone.0046964