Matrine Induces Apoptosis in Human Acute Myeloid Leukemia Cells via the Mitochondrial Pathway and Akt Inactivation

Acute myeloid leukemia (AML) is a hematological malignancy characterized by a rapid increase in the number of immature myeloid cells in bone marrow. Despite recent advances in the treatment, AML remains an incurable disease. Matrine, a major component extracted from Sophora flavescens Ait, has been...

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Detalles Bibliográficos
Autores principales: Zhang, Shenghui, Zhang, Yan, Zhuang, Yan, Wang, Jiajie, Ye, Jianqin, Zhang, Si, Wu, Jianbo, Yu, Kang, Han, Yixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466205/
https://www.ncbi.nlm.nih.gov/pubmed/23056487
http://dx.doi.org/10.1371/journal.pone.0046853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466205/
https://www.ncbi.nlm.nih.gov/pubmed/23056487
http://dx.doi.org/10.1371/journal.pone.0046853

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