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Identification of an Annonaceous Acetogenin Mimetic, AA005, as an AMPK Activator and Autophagy Inducer in Colon Cancer Cells

Annonaceous acetogenins, a large family of naturally occurring polyketides isolated from various species of the plant genus Annonaceae, have been found to exhibit significant cytotoxicity against a variety of cancer cells. Previous studies showed that these compounds could act on the mitochondria co...

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Detalles Bibliográficos
Autores principales: Liu, Yong-Qiang, Cheng, Xin, Guo, Liang-Xia, Mao, Chan, Chen, Yi-Jie, Liu, Hai-Xia, Xiao, Qi-Cai, Jiang, Sheng, Yao, Zhu-Jun, Zhou, Guang-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466238/
https://www.ncbi.nlm.nih.gov/pubmed/23056575
http://dx.doi.org/10.1371/journal.pone.0047049