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Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that induces a battery of cytoprotective genes involved in antioxidant defense through binding to Antioxidant Response Elements (ARE) located in the promoter regions of these genes. To identify Nrf2 activators for the treat...

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Detalles Bibliográficos
Autores principales:	Wu, Kai Connie, McDonald, Peter R., Liu, Jie Jerry, Chaguturu, Rathnam, Klaassen, Curtis D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466241/ https://www.ncbi.nlm.nih.gov/pubmed/23056183 http://dx.doi.org/10.1371/journal.pone.0044686

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