PDGF Suppresses the Sulfation of CD44v and Potentiates CD44v-Mediated Binding of Colon Carcinoma Cells to Fibrin under Flow

Fibrin(ogen) mediates sustained tumor cell adhesion and survival in the pulmonary vasculature, thereby facilitating the metastatic dissemination of tumor cells. CD44 is the major functional fibrin receptor on colon carcinoma cells. Growth factors, such as platelet-derived growth factor (PDGF), induc...

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Detalles Bibliográficos
Autores principales: Alves, Christina S., Konstantopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466257/
https://www.ncbi.nlm.nih.gov/pubmed/23056168
http://dx.doi.org/10.1371/journal.pone.0041472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466257/
https://www.ncbi.nlm.nih.gov/pubmed/23056168
http://dx.doi.org/10.1371/journal.pone.0041472

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