Myb-Binding Protein 1A (MYBBP1A) Is Essential for Early Embryonic Development, Controls Cell Cycle and Mitosis, and Acts as a Tumor Suppressor

MYBBP1A is a predominantly nucleolar transcriptional regulator involved in rDNA synthesis and p53 activation via acetylation. However little further information is available as to its function. Here we report that MYBBP1A is developmentally essential in the mouse prior to blastocyst formation. In ce...

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Detalles Bibliográficos
Autores principales: Mori, Silvia, Bernardi, Rosa, Laurent, Audrey, Resnati, Massimo, Crippa, Ambra, Gabrieli, Arianna, Keough, Rebecca, Gonda, Thomas J., Blasi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466261/
https://www.ncbi.nlm.nih.gov/pubmed/23056166
http://dx.doi.org/10.1371/journal.pone.0039723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466261/
https://www.ncbi.nlm.nih.gov/pubmed/23056166
http://dx.doi.org/10.1371/journal.pone.0039723

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