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Overexpression of HTRA1 Leads to Down-Regulation of Fibronectin and Functional Changes in RF/6A Cells and HUVECs

Multiple genetic studies have suggested that high-temperature requirement serine protease (HTRA1) is associated with polypoidal choroidal vasculopathy (PCV). To date, no functional studies have investigated the biological effect of HTRA1 on vascular endothelial cells, essential vascular components i...

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Detalles Bibliográficos
Autores principales: Jiang, Jingjing, Huang, Lvzhen, Yu, Wenzhen, Wu, Xi, Zhou, Peng, Li, Xiaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466263/
https://www.ncbi.nlm.nih.gov/pubmed/23056244
http://dx.doi.org/10.1371/journal.pone.0046115