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Impact of Cell Type and Epitope Tagging on Heterologous Expression of G Protein-Coupled Receptor: A Systematic Study on Angiotensin Type II Receptor

Despite heterologous expression of epitope-tagged GPCR is widely adopted for functional characterization, there is lacking of systematic analysis of the impact of expression host and epitope tag on GPCR expression. Angiotensin type II (AT2) receptor displays agonist-dependent and -independent activi...

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Detalles Bibliográficos
Autores principales: Jiang, Lili, Teng, Gladys M. K., Chan, Elaine Y. M., Au, Shannon W. N., Wise, Helen, Lee, Susanna S. T., Cheung, Wing-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466278/
https://www.ncbi.nlm.nih.gov/pubmed/23056563
http://dx.doi.org/10.1371/journal.pone.0047016