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The bHLH Repressor Deadpan Regulates the Self-renewal and Specification of Drosophila Larval Neural Stem Cells Independently of Notch

Neural stem cells (NSCs) are able to self-renew while giving rise to neurons and glia that comprise a functional nervous system. However, how NSC self-renewal is maintained is not well understood. Using the Drosophila larval NSCs called neuroblasts (NBs) as a model, we demonstrate that the Hairy and...

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Detalles Bibliográficos
Autores principales: Zhu, Sijun, Wildonger, Jill, Barshow, Suzanne, Younger, Susan, Huang, Yaling, Lee, Tzumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466283/
https://www.ncbi.nlm.nih.gov/pubmed/23056424
http://dx.doi.org/10.1371/journal.pone.0046724