Statins and Selective Inhibition of Rho Kinase Protect Small Conductance Calcium-Activated Potassium Channel Function (K(Ca)2.3) in Cerebral Arteries

BACKGROUND: In rat middle cerebral and mesenteric arteries the K(Ca)2.3 component of endothelium-dependent hyperpolarization (EDH) is lost following stimulation of thromboxane (TP) receptors, an effect that may contribute to the endothelial dysfunction associated with cardiovascular disease. In cere...

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Detalles Bibliográficos
Autores principales: McNeish, Alister J., Jimenez-Altayo, Francesc, Cottrell, Graeme S., Garland, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466297/
https://www.ncbi.nlm.nih.gov/pubmed/23056429
http://dx.doi.org/10.1371/journal.pone.0046735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466297/
https://www.ncbi.nlm.nih.gov/pubmed/23056429
http://dx.doi.org/10.1371/journal.pone.0046735

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