Cargando…

Statins and Selective Inhibition of Rho Kinase Protect Small Conductance Calcium-Activated Potassium Channel Function (K(Ca)2.3) in Cerebral Arteries

BACKGROUND: In rat middle cerebral and mesenteric arteries the K(Ca)2.3 component of endothelium-dependent hyperpolarization (EDH) is lost following stimulation of thromboxane (TP) receptors, an effect that may contribute to the endothelial dysfunction associated with cardiovascular disease. In cere...

Descripción completa

Detalles Bibliográficos
Autores principales:	McNeish, Alister J., Jimenez-Altayo, Francesc, Cottrell, Graeme S., Garland, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466297/ https://www.ncbi.nlm.nih.gov/pubmed/23056429 http://dx.doi.org/10.1371/journal.pone.0046735

Ejemplares similares

Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat
por: McNeish, A.J., et al.
Publicado: (2010)

Regulation of K(Ca)2.3 and endothelium-dependent hyperpolarization (EDH) in the rat middle cerebral artery: the role of lipoxygenase metabolites and isoprostanes
por: Gauthier, Kathryn M., et al.
Publicado: (2014)

Characterisation of the vasodilation effects of DHA and EPA, n-3 PUFAs (fish oils), in rat aorta and mesenteric resistance arteries
por: Limbu, Roshan, et al.
Publicado: (2018)

Omega-3 polyunsaturated fatty acid-induced vasodilation in mouse aorta and mesenteric arteries is not mediated by ATP-sensitive potassium channels
por: Bercea, Cristiana, et al.
Publicado: (2022)

The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor
por: Roux, Benoît T., et al.
Publicado: (2017)

Editorial: Rising stars in vascular physiology: 2022
por: Tulis, David A., et al.
Publicado: (2023)

Suppression of the Rho/Rho-Kinase Pathway and Prevention of Cerebral Vasospasm by Combination Treatment with Statin and Fasudil After Subarachnoid Hemorrhage in Rabbit
por: Naraoka, Masato, et al.
Publicado: (2013)

Oxidative Regulation of Large Conductance Calcium-Activated Potassium Channels
por: Tang, Xiang D., et al.
Publicado: (2001)

The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium
por: King, D. Ryan, et al.
Publicado: (2021)

Fine structural localization of potassium-stimulated rho nitrophenylphosphatase activity in denrites of the cerebral cortex
por: Broderson, S. H., et al.
Publicado: (1978)

Small Resistance Artery Disease and ACE2 in Hypertension: A New Paradigm in the Context of COVID-19
por: Galán, María, et al.
Publicado: (2020)

Rho-GTPase and Atherosclerosis: Pleiotropic Effects of Statins
por: Cai, Anping, et al.
Publicado: (2015)

Calcium-activated potassium conductance in presynaptic terminals at the crayfish neuromuscular junction
Publicado: (1991)

Cardiac small-conductance calcium-activated potassium channels in health and disease
por: Zhang, Xiao-Dong, et al.
Publicado: (2021)

Intermediate-Conductance-Ca2-Activated K Channel Intermediate-Conductance Calcium-Activated Potassium Channel (IKCa1) is Upregulated and Promotes Cell Proliferation in Cervical Cancer
por: Liu, Ling, et al.
Publicado: (2017)

Peptide Lv augments intermediate-conductance calcium-dependent potassium channels (K(Ca)3.1) in endothelial cells to promote angiogenesis
por: Pham, Dylan L., et al.
Publicado: (2022)

Acupuncture ameliorates neurological function in rats with cerebral ischemia‐reperfusion by regulating the opening of large‐conductance Ca(2+)‐activated potassium channels
por: Han, Lin, et al.
Publicado: (2021)

Uric acid therapy for vasculoprotection in acute ischemic stroke
por: Amaro, Sergi, et al.
Publicado: (2019)

Reactive Oxygen Species and Oxidative Stress in the Pathogenesis and Progression of Genetic Diseases of the Connective Tissue
por: Egea, Gustavo, et al.
Publicado: (2020)

Statins Inhibit HIV-1 Infection by Down-regulating Rho Activity
por: del Real, Gustavo, et al.
Publicado: (2004)

Presynaptic facilitation at the crayfish neuromuscular junction. Role of calcium-activated potassium conductance
Publicado: (1991)

Immunolocalization and expression of small-conductance calcium-activated potassium channels in human myometrium
por: Rosenbaum, Sofia T, et al.
Publicado: (2012)

The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception
por: Walcott, Kia C.E., et al.
Publicado: (2018)

Revisiting the Large-Conductance Calcium-Activated Potassium (BKCa) Channels in the Pulmonary Circulation
por: Guntur, Divya, et al.
Publicado: (2021)

Hypoxic Regulation of the Large-Conductance, Calcium and Voltage-Activated Potassium Channel, BK
por: Ochoa, Sara V., et al.
Publicado: (2021)

The role of high‐conductance calcium‐activated potassium channel in headache and migraine pathophysiology
por: Al‐Karagholi, Mohammad Al‐Mahdi, et al.
Publicado: (2022)

Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers
por: Henninger, Christian, et al.
Publicado: (2017)

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I(bk,Ca))
por: Horváth, András, et al.
Publicado: (2020)

Defect Structure and Oxide Ion Conduction of Potassium Ion Substituted CaWO(4)
por: Takai, Shigeomi, et al.
Publicado: (2018)

Vascular Aging: Facts and Factors
por: Dantas, Ana P., et al.
Publicado: (2012)

Mechanisms of diarrhoea
por: Booth, I.W., et al.
Publicado: (1993)

Ion conductance and selectivity of single calcium-activated potassium channels in cultured rat muscle
Publicado: (1984)

Molecular heterogeneity of large-conductance calcium-activated potassium channels in canine intracardiac ganglia
por: Selga, Elisabet, et al.
Publicado: (2013)

Small‐Conductance Calcium‐Activated Potassium Current in Normal Rabbit Cardiac Purkinje Cells
por: Reher, Thomas A., et al.
Publicado: (2017)

Big conductance calcium‐activated potassium channel openers control spasticity without sedation
por: Baker, David, et al.
Publicado: (2017)

External Hemin as an Inhibitor of Mitochondrial Large-Conductance Calcium-Activated Potassium Channel Activity
por: Walewska, Agnieszka, et al.
Publicado: (2022)

Cannabidiol improves survival and behavioural co‐morbidities of Dravet syndrome in mice
por: Patra, Pabitra Hriday, et al.
Publicado: (2020)

Molecular Mechanisms of Large-Conductance Ca(2+)-Activated Potassium Channel Activation by Ginseng Gintonin
por: Choi, S. H., et al.
Publicado: (2013)

LINGO1 is a regulatory subunit of large conductance, Ca(2+)-activated potassium channels
por: Dudem, Srikanth, et al.
Publicado: (2020)

Gating of Recombinant Small-Conductance Ca-activated K(+) Channels by Calcium
por: Hirschberg, Birgit, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_hu2rte13f43sohnc27581m9eru