Neurovirulence of H5N1 Infection in Ferrets Is Mediated by Multifocal Replication in Distinct Permissive Neuronal Cell Regions

Highly pathogenic avian influenza A (HPAI), subtype H5N1, remains an emergent threat to the human population. While respiratory disease is a hallmark of influenza infection, H5N1 has a high incidence of neurological sequelae in many animal species and sporadically in humans. We elucidate the tempora...

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Detalles Bibliográficos
Autores principales: Plourde, Jennifer R., Pyles, John A., Layton, R. Colby, Vaughan, Sarah E., Tipper, Jennifer L., Harrod, Kevin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466300/
https://www.ncbi.nlm.nih.gov/pubmed/23056366
http://dx.doi.org/10.1371/journal.pone.0046605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466300/
https://www.ncbi.nlm.nih.gov/pubmed/23056366
http://dx.doi.org/10.1371/journal.pone.0046605

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