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Neurovirulence of H5N1 Infection in Ferrets Is Mediated by Multifocal Replication in Distinct Permissive Neuronal Cell Regions
Highly pathogenic avian influenza A (HPAI), subtype H5N1, remains an emergent threat to the human population. While respiratory disease is a hallmark of influenza infection, H5N1 has a high incidence of neurological sequelae in many animal species and sporadically in humans. We elucidate the tempora...
Autores principales: | Plourde, Jennifer R., Pyles, John A., Layton, R. Colby, Vaughan, Sarah E., Tipper, Jennifer L., Harrod, Kevin S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466300/ https://www.ncbi.nlm.nih.gov/pubmed/23056366 http://dx.doi.org/10.1371/journal.pone.0046605 |
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