Acute Reactogenicity after Intramuscular Immunization with Recombinant Vesicular Stomatitis Virus Is Linked to Production of IL-1β

Vaccines based on live viruses are attractive because they are immunogenic, cost-effective, and can be delivered by multiple routes. However, live virus vaccines also cause reactogenic side effects such as fever, myalgia, and injection site pain that have reduced their acceptance in the clinic. Seve...

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Detalles Bibliográficos
Autores principales: Athearn, Kathleen, Sample, Christopher J., Barefoot, Brice E., Williams, Kristi L., Ramsburg, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466325/
https://www.ncbi.nlm.nih.gov/pubmed/23056330
http://dx.doi.org/10.1371/journal.pone.0046516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466325/
https://www.ncbi.nlm.nih.gov/pubmed/23056330
http://dx.doi.org/10.1371/journal.pone.0046516

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