Towards quantitative metagenomics of wild viruses and other ultra-low concentration DNA samples: a rigorous assessment and optimization of the linker amplification method

Metagenomics generates and tests hypotheses about dynamics and mechanistic drivers in wild populations, yet commonly suffers from insufficient (< 1 ng) starting genomic material for sequencing. Current solutions for amplifying sufficient DNA for metagenomics analyses include linear amplification...

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Detalles Bibliográficos
Autores principales: Duhaime, Melissa B, Deng, Li, Poulos, Bonnie T, Sullivan, Matthew B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466414/
https://www.ncbi.nlm.nih.gov/pubmed/22713159
http://dx.doi.org/10.1111/j.1462-2920.2012.02791.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466414/
https://www.ncbi.nlm.nih.gov/pubmed/22713159
http://dx.doi.org/10.1111/j.1462-2920.2012.02791.x

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