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Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

BACKGROUND & AIMS: Hyperplasia of mucin-secreting intestinal goblet cells accompanies a number of enteric infections, including infections by nematode parasites. Nevertheless, the precise role of mucins in host defense in nematode infection is not known. We investigated the role of the mucin (Mu...

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Detalles Bibliográficos
Autores principales: Hasnain, Sumaira Z., Wang, Huaqing, Ghia, Jean–Eric, Haq, Nihal, Deng, Yikang, Velcich, Anna, Grencis, Richard K., Thornton, David J., Khan, Waliul I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466424/
https://www.ncbi.nlm.nih.gov/pubmed/20138044
http://dx.doi.org/10.1053/j.gastro.2010.01.045