Impaired apoptosis of megakaryocytes and bone marrow mononuclear cells in essential thrombocythemia: correlation with JAK2V617F mutational status and cytoreductive therapy

Essential thrombocythemia (ET) is a clonal myeloproliferative disorder characterized by overproduction of megakaryocytes (MKCs) and platelets. The recent discovery of the JAK2 mutation has shed a new light on the development of ET but its pathogenesis still remains unknown. One of the possible mecha...

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Detalles Bibliográficos
Autores principales: Treliński, Jacek, Chojnowski, Krzysztof, Cebula-Obrzut, Barbara, Smolewski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466431/
https://www.ncbi.nlm.nih.gov/pubmed/22418850
http://dx.doi.org/10.1007/s12032-012-0202-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466431/
https://www.ncbi.nlm.nih.gov/pubmed/22418850
http://dx.doi.org/10.1007/s12032-012-0202-3

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