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Impaired apoptosis of megakaryocytes and bone marrow mononuclear cells in essential thrombocythemia: correlation with JAK2V617F mutational status and cytoreductive therapy

Essential thrombocythemia (ET) is a clonal myeloproliferative disorder characterized by overproduction of megakaryocytes (MKCs) and platelets. The recent discovery of the JAK2 mutation has shed a new light on the development of ET but its pathogenesis still remains unknown. One of the possible mecha...

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Detalles Bibliográficos
Autores principales:	Treliński, Jacek, Chojnowski, Krzysztof, Cebula-Obrzut, Barbara, Smolewski, Piotr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2012
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466431/ https://www.ncbi.nlm.nih.gov/pubmed/22418850 http://dx.doi.org/10.1007/s12032-012-0202-3

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