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Layer 6 cortical neurons require Reelin-Dab1 signaling for cellular orientation, Golgi deployment, and directed neurite growth into the marginal zone

BACKGROUND: The secreted ligand Reelin is believed to regulate the translocation of prospective layer 6 (L6) neocortical neurons into the preplate, a loose layer of pioneer neurons that overlies the ventricular zone. Recent studies have also suggested that Reelin controls neuronal orientation and po...

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Detalles Bibliográficos
Autores principales: O’Dell, Ryan S, Ustine, Candida J M, Cameron, David A, Lawless, Sean M, Williams, Rebecca M, Zipfel, Warren R, Olson, Eric C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466444/
https://www.ncbi.nlm.nih.gov/pubmed/22770513
http://dx.doi.org/10.1186/1749-8104-7-25